TissueArry.Com provides normal, malignant or metastatic tissue array or tissue microarray (TMA) which can be utilized to validate clinical relevance of potential biological targets in the development of therapeutics, diagnostics and study new protein markers and genes. TMA contains multiple tissue samples with DNA, RNA and protein. The advantage of TMA lies in the small size, and the tissue morphology and genetic characteristics are similar in the serial TMA tissue sections. Therefore, it provides a high-throughput methods for the fast analysis of molecular markers associated with disease diagnosis, prognosis and therapeutics in patients.
TissueArry.Com is offering immunohistochemistry (IHC) staining service and High Resolution TMA Image Scanning & Analysis service.
IHC and ISH
Immunohistochemistry (IHC) and in situ hybridization (ISH) services are provided to customers with specific needs for tissue array experiments. These analyses are performed to localize the protein/gene of interest by using customer-supplied antibodies, DNA fragments or oligonucleotides on normal and diseased human tissues selected from TissueArry.Com's vast selection of tissue arrays.
Image Scanning & Analysis
TissueArry.Com offers the use of Visiopharm for powerful and customizable image analysis. The following services are available for routine analysis:
- Automated quantification of cytoplasm, membrane, or nucleus staining
- Virtual double/triple staining by aligning features on individual cores. Applications include co-localization studies, and automated quantification of tumor regions only.
- A wide variety of algorithms for specific biomarkers shared by others at the Visiopharm App Center